An Improved Model for IBD Drug Discovery

Animal models have been used for years to provide proof of concept for new therapies, however there are major flaws which need to be addressed. Studies using mouse models cannot accurately predict patient response to a new compound. Translatability requires a suitable model which will reduce attrition rates in phase II and III clinical trials which are proving to be of detriment to R&D productivity[1].

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On the right path to a cure for IBD

Advances in diagnostics, treatments, and frontiers of research

In light of World Digestive Disease Day, which is celebrated every year on the 29th of May[1], we will explore the different facets of Inflammatory bowel disease (IBD) and highlight recent advances on the diagnostics, treatments, and the frontiers of research that will one day hopefully provide a cure.

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The gut microbiome in health and disease: the future for diagnosis and treatment of IBD and IBS?

A new method for distinguishing between IBD (inflammatory bowel disease) and IBS (irritable bowel syndrome) could be on the horizon following a publication by researchers from teams in the Netherlands and the US, who profiled the gut microbiome in stool samples from those with IBD, IBS and healthy controls.

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