Drug Discovery

    Predicting Psoriasis Drug Efficacy in Human Skin [Infographic]

    Zara Puckrin / 17 September 2020

    Testing your dermatological treatments in human skin can accelerate lead optimization. But how are models using human tissue established?

    In this infographic, we demonstrate how scientists at REPROCELL (Biopta) helped one Pharma company accelerate the optimization of their lead Psoriasis compound . By using human fresh skin, the researchers were able to determine the optimal concentration of the Psoriasis treatment, and confirm whether it could reduce inflammation. Read on to discover the aims and methodology behind this study.

    Inflammatory Skin Assays - Psoraisis

    In Summary

    In this infographic, we have summarized the aims, methods, and findings of a study using human fresh tissue. Through the initial pilot study, REPROCELL (Biopta) were able to estimate the optimal concentration of the compound for use in Phase 2; which included healthy and diseased skin biopsies from Psoriasis donors.

    Download REPROCELL's (Biopta) skin explant brochure to find out more about our healthy, induced-phenotype, and diseases human skin models.

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