The gut microbiome in health and disease: the future for diagnosis and treatment of IBD and IBS?

A new method for distinguishing between IBD (inflammatory bowel disease) and IBS (irritable bowel syndrome) could be on the horizon following a publication by researchers from teams in the Netherlands and the US, who profiled the gut microbiome in stool samples from those with IBD, IBS and healthy controls.

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Tissue Sourcing for the Development of iPSC-derived Disease Models

Human induced pluripotent stem cells (iPSCs)-based models are an ideal resource for studying disease mechanisms in vitro at the cellular level[1], screening potential new therapeutics[2], and investigating the propensity and mechanism for the development of toxic side effects caused by drug treatment[3]. Such iPSC-based models enable studies to be performed under defined experimental conditions and in a reproducible manner.

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Appointment of New Distributor in China

The REPROCELL group has signed a non-exclusive distributorship agreement with RUITAI Biotechnology (Shanghai) Ltd to distribute REPROCELL’s products in China.

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TISSUE SPOTLIGHT: Skin

In this issue, we are casting the REPROCELL Tissue Spotlight on the SKIN.

In humans, the largest organ in the body is the skin layer, accounting for up to 15% of the total body weight and a surface area of up to 2m2. It is composed of several layers — the epidermis, dermis and the sub-cutaneous layer, the hypodermis — each crucial to the many functions of the skin ranging from a protective barrier for internal tissues and organs, through regulation of body temperature and nutrient absorption, to the generation of vitamin D.

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TISSUE SPOTLIGHT: Intestines

In this issue, we are casting the REPROCELL Tissue Spotlight on the INTESTINES.

The intestines (large and small) are vital organs in the gastrointestinal tract of our digestive system. Comprising a winding muscular tube extending from the stomach to the anus the main purpose is to digest food and absorb nutrients. The intestines also have a key role to play in the processes of cellular messaging, fighting infection and in regulating the body’s water balance.

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The importance of internships for life science students

If you are a science student nearing the end of your university program, developing your professional network in order to land a good job is a daunting task.  In this video, Zara Puckrin and Karen Bingham talk about Zara's experience interning at REPROCELL's Glasgow research lab and the benefits of internships for university students.

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Press Release: ROSLINCT and REPROCELL awarded £1.2 million from Innovate UK for clinical-grade stem cell production

Funding will be used to improve efficiency of induced pluripotent stem cell production

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From Frying-Pan to Fire

How can industry inspire the next generation of life science professionals?  Summer intern Zara Puckrin describes the challenges faced by today’s graduates and explains how REPROCELL have helped her to bridge the gap between university and work.

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The Human Touch: meeting clinical needs in IBD research

There is a clinical need for novel therapies in Inflammatory Bowel Disease. Current research is however limited by models which do not physiologically mimic the disease in humans. REPROCELL’s Human IBD Fresh Tissue Assay is the most clinically relevant IBD model on the market and the only commercially available assay of its kind.

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New publication by Roche on diarrheal toxicity induced by anti-HER2/3 combination therapy includes REPROCELL human fresh tissue data

A publication in Molecular Cancer Therapeutics has shed new light on the mechanisms by which anti-HER2/3 combination therapies can cause diarrhea.

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